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Text File  |  1987-10-07  |  586b  |  16 lines
  1.  
  2.          IN PATIENTS WITH RENAL IMPAIRMENT, DOXYCYCLINE DOSAGE SHOULD
  3.          BE CAREFULLY ADJUSTED TO AVOID TOXICITY (ACIDOSIS, INCREASED
  4.          CATABOLISM).
  5.           
  6.          SOME CLINICIANS RECOMMEND THAT THE DOSAGE REGIMEN BE
  7.          ADJUSTED BASED ON THE PATIENT'S CREATININE CLEARANCE:
  8.           
  9.                       CREATININE     DOSAGE INTERVAL
  10.                        CLEARANCE         METHOD
  11.                       (ML/MINUTE)
  12.           
  13.                         10-50        12 to 18 hours
  14.                          <10         18 to 24 hours
  15.           
  16.